Rapid-progressive Glomerulonephritis (RPGN) – Nephritisches Syndrom
Über den Vortrag
Der Vortrag „Rapid-progressive Glomerulonephritis (RPGN) – Nephritisches Syndrom“ von Amy Sussman, MD ist Bestandteil des Kurses „Nephritisches Syndrom“.
Quiz zum Vortrag
Which of the following is true regarding anti-GBM syndrome?
- It is caused by antibodies directed against type IV collagen in the glomerular basement membrane.
- Younger patients are more likely to present with isolated glomerulonephritis.
- The clinical presentation of Goodpasture's syndrome involves the upper respiratory tract, lungs, and kidneys.
- Biopsy of the kidney typically reveals pauci-immune glomerulonephritis.
Which of the following is true regarding granulomatosis with polyangiitis?
- It is associated with autoantibodies against proteinase 3.
- It is a large-vessel vasculitis and has a preference for the aortic arch and its branches.
- It is associated with autoantibodies against p-ANCA.
- Immunofluorescence microscopy demonstrates linear deposition of IgG along the glomerular basement membrane.
- It is a common cause of immune complex-mediated RPGN.
Which of the following is categorized as a type II, rapidly progressive glomerulonephritis?
- Postinfectious glomerulonephritis
- Dense deposit disorder
- Microscopic polyangiitis
- Anti-GBM syndrome
- Minimal change disease
Which of the following is used in the maintenance phase of the management of RPGN?
- Azathioprine
- Plasmapheresis
- High-dose IV methylprednisolone
- Antibiotics
- Proteosome inhibitors
Which of the following pairings is correct?
- Microscopic polyangiitis － Anti-myeloperoxidase antibodies
- Lupus nephritis － C3 nephritic factor
- Membranoproliferative glomerulonephritis － Anti-phospholipase 2 receptor antibodies
- Membranous nephropathy － Anti–proteinase 3 antibodies
- IgA nephropathy － Anti–double-stranded DNA antibodies
Which of the following statements is true regarding rapidly progressive glomerulonephritis?
- It is characterized morphologically by necrosis and crescent formation on biopsy.
- It can be managed conservatively through a low-salt diet, loop diuretics, and ACE inhibitors/ARBs.
- It is a type of severe acute nephrotic syndrome.
- The findings on biopsy develop over a prolonged period of time.
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Dozent des Vortrages Rapid-progressive Glomerulonephritis (RPGN) – Nephritisches Syndrom
Amy Sussman, MD
Dr. Amy Sussman is an Associate Professor of Medicine and the Vice Chair of Education in the Department of Medicine of the University of Arizona (UA), USA.
She obtained her MD from the University of Arizona in 2001 and completed residency and a Nephrology Fellowship at the University of Washington. Dr. Sussman was recruited back to the UA in 2009 and also serves as her department's clerkship director, and as the program director of the UA Nephrology Fellowship.
Because of her strong emphasis on medical student teaching, she has been distinguished with multiple teaching awards in the UA College of Medicine.
Within Lecturio, Dr. Sussman teaches courses on Nephrology.
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