Membranöse Nephropathie – Nephrotisches Syndrom
Über den Vortrag
Der Vortrag „Membranöse Nephropathie – Nephrotisches Syndrom“ von Amy Sussman, MD ist Bestandteil des Kurses „Nephrotisches Syndrom“.
Quiz zum Vortrag
Which of the following is involved in the pathogenesis of primary membranous nephropathy?
- Autoantibodies to phospholipase A2 receptors
- Autoantibodies to glutamic acid decarboxylase
- Autoantibodies to type IV collagen
- Autoantibodies to structures within the nucleus
- Mismatch repair deficiency
Which of the following is compatible with a diagnosis of membranous nephropathy?
- Normal complement levels
- Low C3 and C4 levels
- Low C4 levels only
- Granular casts on urinalysis
- Microproteinuria
Which of the following is true regarding the histopathology of membranous nephropathy?
- Light microscopy reveals a spike-and-dome pattern.
- Immunofluorescence microscopy reveals a linear pattern of immunoglobulin deposition.
- Immunofluorescence microscopy reveals characteristic pauci-immune staining.
- Electron microscopy reveals mesangial deposits.
Which of the following predicts the progression of membranous nephropathy to ESRD?
- Tubulointerstitial fibrosis
- A serum protein level of >8 mg
- Female sex
- Young age
- Low serum creatinine level
Which of the following is part of the immune-targeted treatment for membranous nephropathy?
- Rituximab
- Low-salt diet
- ACE inhibitors
- Statins
- Loop diuretics
Which of the following is true about membranous nephropathy?
- Spontaneous remission is defined as <200 mg of proteinuria per day.
- Light microscopy reveals duplication of the basement membrane.
- Hodgkin lymphoma is commonly associated with membranous nephropathy.
- Immunosuppressive therapy is the first-line treatment.
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Dozent des Vortrages Membranöse Nephropathie – Nephrotisches Syndrom
Amy Sussman, MD
Dr. Amy Sussman is an Associate Professor of Medicine and the Vice Chair of Education in the Department of Medicine of the University of Arizona (UA), USA.
She obtained her MD from the University of Arizona in 2001 and completed residency and a Nephrology Fellowship at the University of Washington. Dr. Sussman was recruited back to the UA in 2009 and also serves as her department's clerkship director, and as the program director of the UA Nephrology Fellowship.
Because of her strong emphasis on medical student teaching, she has been distinguished with multiple teaching awards in the UA College of Medicine.
Within Lecturio, Dr. Sussman teaches courses on Nephrology.
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