Lupus-Nephritis – Nephritisches Syndrom
Über den Vortrag
Der Vortrag „Lupus-Nephritis – Nephritisches Syndrom“ von Amy Sussman, MD ist Bestandteil des Kurses „Nephritisches Syndrom“.
Quiz zum Vortrag
Which of the following is involved in the pathogenesis of lupus nephritis?
- Autoantibodies against nucleosomes
- Inappropriate activation of the alternative complement pathway
- Autoantibodies to type IV collagen in the glomerular basement membrane
- Persistent HCV antigenemia
- Autoantibodies that stabilize C3 convertase
Which of the following is associated with lupus nephritis?
- Anti-dsDNA antibodies
- Normal C3 and C4 complement levels
- Decreased AH50
- Bland urinary sediments
- Anti–cyclic citrullinated peptide (CCP) antibodies
Which of the following differentiates membranous lupus nephritis from classical membranous nephropathy?
- Mesangial hypercellularity on renal biopsy
- Low C3, C4, and total CH50 complement levels
- Active urinary sediment with RBC casts
- Abnormal serologic testing results
A renal biopsy of a patient with SLE shows inflammatory injury involving >50% of glomeruli. What is the classification of this patient's lupus nephritis?
- Class IV, diffuse lupus nephritis
- Class II, mesangial proliferative lupus nephritis
- Class III, focal lupus nephritis
- Class V, membranous lupus nephritis
- Class VI, advanced sclerosis lupus nephritis
Which of the following is true regarding the management of lupus nephritis?
- Induction therapy should consist of glucocorticoids combined with either cyclophosphamide or mycophenolate mofetil.
- Aggressive immunosuppressive therapy is indicated in patients with lupus nephritis class IV, V, or VI.
- Induction therapy for lupus nephritis consists of glucocorticoid monotherapy.
- Mycophenolate mofetil, which is an anti-CD20 antibody, is the preferred choice for maintenance therapy.
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Dozent des Vortrages Lupus-Nephritis – Nephritisches Syndrom
Amy Sussman, MD
Dr. Amy Sussman is an Associate Professor of Medicine and the Vice Chair of Education in the Department of Medicine of the University of Arizona (UA), USA.
She obtained her MD from the University of Arizona in 2001 and completed residency and a Nephrology Fellowship at the University of Washington. Dr. Sussman was recruited back to the UA in 2009 and also serves as her department's clerkship director, and as the program director of the UA Nephrology Fellowship.
Because of her strong emphasis on medical student teaching, she has been distinguished with multiple teaching awards in the UA College of Medicine.
Within Lecturio, Dr. Sussman teaches courses on Nephrology.
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