Fokal-segmentale Glomerulosklerose (FSGS) – Nephrotisches Syndrom
Über den Vortrag
Der Vortrag „Fokal-segmentale Glomerulosklerose (FSGS) – Nephrotisches Syndrom“ von Amy Sussman, MD ist Bestandteil des Kurses „Nephrotisches Syndrom“.
Quiz zum Vortrag
Which of the following is involved in the pathogenesis of primary focal segmental glomerulosclerosis?
- Mutations in slit diaphragm proteins
- Mutations in hemoglobin proteins
- Infection with a retrovirus
- Drug-induced podocyte damage
Which of the following is true regarding the clinical manifestations of FSGS?
- Secondary FSGS rarely presents with edema and hypoalbuminemia.
- Primary FSGS always has an insidious onset.
- Both subtypes of FSGS frequently present with nephrotic range proteinuria and lipiduria.
- Patients with primary FSGS have low C3 and C4 levels.
Which of the following histopathological changes is associated with FSGS?
- Electron microscopy reveals effacement of the podocyte foot processes.
- Light microscopy reveals fibrosis that involves > 50% of glomeruli.
- Fluorescence microscopy reveals a linear distribution of antibodies along the basement membrane.
- Light microscopy reveals the formation of spikes and domes in the basement membrane.
Which of the following is true regarding the management of FSGS?
- Familial FSGS can be cured with renal transplants.
- Blood pressure should be maintained below 140/90 mm Hg
- ACE inhibitors/ARBs are not indicated for the initial episode of FSGS.
- Cyclophosphamide is the first-line immune-targeted treatment for FSGS.
Which of the following predicts a poor prognosis in FSGS?
- Tubulointerstitial fibrosis on renal biopsy
- Young age
- Responsive to prednisolone
- Proteinuria > 3.5 g/day
- Plasma creatinine concentration < 1.3 mg/dL
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Dozent des Vortrages Fokal-segmentale Glomerulosklerose (FSGS) – Nephrotisches Syndrom
Amy Sussman, MD
Dr. Amy Sussman is an Associate Professor of Medicine and the Vice Chair of Education in the Department of Medicine of the University of Arizona (UA), USA.
She obtained her MD from the University of Arizona in 2001 and completed residency and a Nephrology Fellowship at the University of Washington. Dr. Sussman was recruited back to the UA in 2009 and also serves as her department's clerkship director, and as the program director of the UA Nephrology Fellowship.
Because of her strong emphasis on medical student teaching, she has been distinguished with multiple teaching awards in the UA College of Medicine.
Within Lecturio, Dr. Sussman teaches courses on Nephrology.
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