Parkinson-Plus-Syndrome: Multisystematrophie
Über den Vortrag
Der Vortrag „Parkinson-Plus-Syndrome: Multisystematrophie“ von Roy Strowd, MD ist Bestandteil des Kurses „Klinische Neurologie“.
Quiz zum Vortrag
Which of the following diseases can be described as a rapidly progressive, multisystem disease that is characterized by parkinsonian features, autonomic dysfunction, and corticospinal disorders?
- Multiple system atrophy
- Lewy body dementia
- Parkinson disease
- Alzheimer disease
- Corticobasal degeneration
What category of neurodegenerative disease does multiple system atrophy (MSA) come under?
- Alpha-synucleinopathy
- B-amyloidopathy
- Tauopathy
- Prion disease
What is the proposed pathophysiologic mechanism of multiple system atrophy?
- Neurons spread aberrant alpha-synuclein to glial cells, leading to an inflammatory cascade.
- Alpha-synuclein deposits in the brainstem and basal ganglia, leading to autolysis.
- Amyloid infiltrates the gray matter, creating a nidus for alpha-synuclein binding.
- Alpha-synuclein mediates degeneration of the frontal and temporal regions of the brain.
Which of the following symptoms is commonly found in multiple system atrophy (MSA)?
- Both erectile dysfunction and orthostatic hypotension
- Hallucinations
- Erectile dysfunction
- Orthostatic hypotension
- Both orthostatic hypotension and hallucinations
What might one see on MRI imaging in a patient with moderate-to-severe MSA?
- Subcortical brainstem and cerebellar atrophy
- Frontal and temporal lobe atrophy
- Frontal and parietal lobe atrophy
- Biventricular enlargement
Which of the following is a pharmacologic management option for orthostatic hypotension in patients with MSA?
- Fludrocortisone
- Epinephrine
- Phenylephrine
- Propranolol
- Ginkgo biloba
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Dozent des Vortrages Parkinson-Plus-Syndrome: Multisystematrophie
Roy Strowd, MD
Dr. Roy Strowd is the Assistant Dean of Undergraduate Medical Education at the Wake Forest Baptist Medical Center, in North Carolina, USA.
He obtained his MD from Wake Forest School of Medicine in 2009, and his MEd from Johns Hopkins University in 2021. Currently, he co-directs the Neurofibromatosis and Tuberous Sclerosis Clinics at Wake Forest Baptist Medical Center, and is a researcher for the Adult Brain Tumor Consortium (ABTC) and Alliance for Clinical Trials in Neuro-Oncology.
Due to his achievements, he earned the M. Brownell Anderson Award from the Association of American Medical Colleges.
Within Lecturio, Dr. Strowd teaches courses on Clinical Neurology.
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