Alzheimer-Demenz: Pathophysiologie
Über den Vortrag
Der Vortrag „Alzheimer-Demenz: Pathophysiologie“ von Roy Strowd, MD ist Bestandteil des Kurses „Alzheimer-Demenz“.
Quiz zum Vortrag
What are the two most important proteins thought to be implicated in the pathophysiologic mechanisms that lead to the development of Alzheimer disease?
- Beta-amyloid and tau
- Prions and tau
- Alpha-synuclein and beta-amyloid
- Alpha-synuclein and neurofibrillary tangles
What protein, when cleaved, produces beta-amyloid protein?
- APP (amyloid-beta precursor protein)
- Tau
- Alpha-synuclein
- CAP (cerebral amyloid protein)
What function does tau serve in healthy brain tissue?
- Binds to and stabilizes microtubules, thereby assisting in microtubule assembly and stabilization
- Assists in the migration of lipid-soluble protein precursors across the neuronal cell membrane
- Facilitates proper folding of beta-amyloid protein and breakdown of misfolded plaques
- Binds to ribosomal subunits and allows for transcription of membrane transporter proteins
What is the tertiary structure (conformation) of a misfolded aggregate of beta-amyloid protein?
- Plaques
- Neurofibrillary tangles
- Alpha-helices
- Zinc fingers
- Double helices
What is the tertiary structure (conformation) of a misfolded aggregate of tau protein?
- Neurofibrillary tangles
- Plaques
- Reticulated networks
- Sheets
- Icosahedrons
Diese Kurse könnten Sie interessieren
Dozent des Vortrages Alzheimer-Demenz: Pathophysiologie
Roy Strowd, MD
Dr. Roy Strowd is the Assistant Dean of Undergraduate Medical Education at the Wake Forest Baptist Medical Center, in North Carolina, USA.
He obtained his MD from Wake Forest School of Medicine in 2009, and his MEd from Johns Hopkins University in 2021. Currently, he co-directs the Neurofibromatosis and Tuberous Sclerosis Clinics at Wake Forest Baptist Medical Center, and is a researcher for the Adult Brain Tumor Consortium (ABTC) and Alliance for Clinical Trials in Neuro-Oncology.
Due to his achievements, he earned the M. Brownell Anderson Award from the Association of American Medical Colleges.
Within Lecturio, Dr. Strowd teaches courses on Clinical Neurology.
Kundenrezensionen
5,0 von 5 Sternen
| 5 Sterne |
|
5 |
| 4 Sterne |
|
0 |
| 3 Sterne |
|
0 |
| 2 Sterne |
|
0 |
| 1 Stern |
|
0 |
