Nucleotide Metabolism: Introduction and De novo Purine Metabolism
Über den Vortrag
Der Vortrag „Nucleotide Metabolism: Introduction and De novo Purine Metabolism“ von Kevin Ahern, PhD ist Bestandteil des Kurses „Year 1 – Term 2 – Basic Principles of Medicine II – Endocrinology and Reproduction“. Der Vortrag ist dabei in folgende Kapitel unterteilt:
- Nucleotide Metabolism - Introduction
- De novo Purine Metabolism
- Building a Purine Ring
Quiz zum Vortrag
Which of the following are true regarding nucleotides? Select all that apply
- They are made by de novo and salvage pathways.
- They are made in separate, non-overlapping pathways for each nucleotide.
- They can have any of three purines or two pyrimidines.
- Structurally, pyrimidines have two rings, and purines have one.
- They are the building blocks of DNA and RNA.
Which of the following is true regarding purine synthesis?
- All of the answers are true.
- PRPP synthetase catalyzes the process that converts ATP to AMP.
- It begins with ribose-5-phosphate.
- It includes the intermediate known as IMP.
- It consumes ATP.
Which of the following does NOT take part in ATP and GTP synthesis?
- Gluteraldehyde
- Glycine and glutamine
- CO2
- Aspartate
- N10-formyl-THF
Which of the following is NOT correctly associated regarding ATP and GTP synthesis?
- N10-formyl-THF — source of N atoms in purine synthesis
- Ribose-5-phosphate — starting point
- Inosine monophosphate — branch point between ATP and GTP synthesis
- PRPP synthetase — regulatory enzyme for purine synthesis
- PRPP amidotransferase — helpful in synthesis of phosphoribosylamine
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Dozent des Vortrages Nucleotide Metabolism: Introduction and De novo Purine Metabolism
Kevin Ahern, PhD
Dr. Kevin Ahern is a Professor in the Department of Biochemistry and Biophysics at Oregon State University (OSU), USA.
He obtained his PhD in Biochemistry from Oregon State University. Currently, he teaches courses for health sciences students at OSU.
He is co-author of three Open Educational electronic textbooks on Biochemistry and a Guide to Getting Into Medical School.
Due to his achievements, he earned OSU’s highest teaching recognition, the Elizabeth P. Ritchie Distinguished Professor Award in 2017.
Within Lecturio, Dr. Ahern teaches courses on Biochemistry and on "How to Get into Medical School”.
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Thanks for focusing on the "big picture!" The lecturer at my school bogged us down with the details, so it was hard to take in what the most important steps were
