Depression: Definition and Pathogenesis
Über den Vortrag
Der Vortrag „Depression: Definition and Pathogenesis“ von Helen Farrell, MD ist Bestandteil des Kurses „Year 4 – Selective Sub-Internship“. Der Vortrag ist dabei in folgende Kapitel unterteilt:
- Depression
- Depression - Pathogenesis
- Hippocampus
Quiz zum Vortrag
Which of the following statements about depression is NOT true?
- It’s is more common in African American females.
- About 10-15% commit suicide
- Sigmund Freud described depression as anger turned inward
- Only half of the patient receive treatment
- Females experience it 1.5-3 times more than in males
Which of the following neurotransmitter changes are seen in depression?
- ↓serotonin, ↓norepinephrine, ↓dopamine
- ↓serotonin, ↑norepinephrine, ↓dopamine
- ↓serotonin, ↑norepinephrine, ↑dopamine
- ↑serotonin, ↑norepinephrine, ↓dopamine
- ↑serotonin, ↑norepinephrine, ↑dopamine
According to the monoamine hypothesis, what is the mechanism of action of antidepressants?
- Antidepressants increase the concentration of NE and serotonin in the synapse and downregulate the post-synaptic receptors.
- Antidepressants increase the concentration of NE and serotonin in the synapse by downregulating the pre-synaptic receptors
- Antidepressants decrease the concentration of NE and serotonin in the synapse and downregulate the post-synaptic receptors.
- Antidepressants decrease the concentration of NE and serotonin in the synapse by upregulating the postsynaptic receptors.
- Antidepressants increase the concentration of NE and serotonin in the synapse and upregulate the pre-synaptic receptors.
What changes are seen in the Hippocampus during depression?
- Elevated cortisol during stress is neurotoxic to the Hippocampus.
- Decreased dopamine affects the functionality of the Hippocampus.
- Elevated concentrations of NE acts as a neurotoxic agent on the Hippocampus.
- Cortisol level falls during the times of stress and impairs the functions of the Hippocampus.
- Elevated serotonin is neurotoxic to the Hippocampus.
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Dozent des Vortrages Depression: Definition and Pathogenesis
Helen Farrell, MD
Dr. Helen M. Farrell is a board-certified psychiatrist and works in private practice in Boston MA. She obtained her MD from Trinity College Dublin, Ireland in 2006. Dr. Farrell served on the Harvard Medical School faculty for over a decade, during which time she was an award-winning lecturer.
Due to her achievements, she is well-published in the field of psychiatry and forensic psychiatry and has appeared as an expert witness in court. She also delivered the TEDx Talk, “Creating Hope for Mental Health” in 2015 and has since contributed to multiple TED-Ed videos on mental health, which have over 30 million collective views.
Within Lecturio, Dr. Farrell teaches courses on Psychiatry.
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I found the class to be very detailed and informative.
Content is ok, but she reads off the slides almost verbatim which is distracting and unhelpful. It would be better if there were fewer words on each slide. I'mn sure this isn't the case, but I get the impression that she doesn't have a solid grasp of the content, hence the slide reading line by line.
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