Mediation of Antigen Receptor Genetic Recombination – Lymphocyte Development
Über den Vortrag
Der Vortrag „Mediation of Antigen Receptor Genetic Recombination – Lymphocyte Development“ von Peter Delves, PhD ist Bestandteil des Kurses „Adaptive Immune System“. Der Vortrag ist dabei in folgende Kapitel unterteilt:
- Mediation of the Genetic Recombination
- Genetic Recombination of the Heavy Chain
Quiz zum Vortrag
During V(D)J recombination in immature B cells, recombination signal sequences are recognized by which of the following?
- Recombination-activating gene 1/Recombination-activating gene 2 enzymes
- Diversity regions
- Leading regions
- Constant regions
- Joining regions
Which of the following is NOT true regarding Recombination-activating gene 1/Recombination-activating gene 2 enzymes?
- They translate recombination signal sequences.
- They mediate recombination of immunoglobulin genes.
- They mediate both heavy and light chain recombination.
- They recognize recombination signal sequence (RSS) nucleotides.
- They regulate the expression of the V, D, and J segments.
Genetic recombination of the immunoglobulin heavy and light chains occur in a specific sequence. Which of the following most accurately reflects that sequence?
- Recombination of the VDJ segments of the heavy chains followed by the VJ segments of the light chains
- Recombination of the VJ segments of the heavy chains followed by the VDJ segments of the light chains
- Recombination of the VDJ segments of the light chains followed by the VJ segments of the heavy chains
- Recombination of the VDJ segments of the light chains followed by the VDJ segments of the heavy chains
- Recombination of the VJ segments of the light chains followed by the VJ segments of the heavy chains
Which of the following combinations of light and/or heavy chains typically constitutes a complete antibody?
- 2 heavy chains and 2 light chains
- 2 heavy chains or 2 light chains
- 1 heavy chain and 1 light chain
- 1 heavy chain and 2 light chains
- Any combination is possible.
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Dozent des Vortrages Mediation of Antigen Receptor Genetic Recombination – Lymphocyte Development
Peter Delves, PhD
Dr. Peter Delves is a Professor Emeritus of Immunology and served as the Vice Dean of Education of the Faculty of Medical Sciences at University College London, UK.
He obtained his PhD at the University of London and is a prolific author, having published several textbooks and laboratory manuals. He is also the editor of two encyclopedias on immunology and on life sciences.
Dr. Delves has extensive teaching experience at both the undergraduate and postgraduate levels and is particularly interested in innovations in web-based education.
Within Lecturio, Dr. Delves teaches courses on the Immune System.
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