Pyrimidine de novo Metabolism: ATCase Reaction
Über den Vortrag
Der Vortrag „Pyrimidine de novo Metabolism: ATCase Reaction“ von Kevin Ahern, PhD ist Bestandteil des Kurses „Purine and Pyrimidine Metabolism“.
Quiz zum Vortrag
The amount of pyrimidine is controlled by which enzyme?
- ATCase
- PRPP synthetase
- PRPP amidotransferase
- IMP dehydrogenase
- Adenylosuccinate synthetase
The ATCase enzyme is activated due to an excess of which of the following?
- ATP and aspartate
- CTP and aspartate
- GTP and aspartate
- UTP and aspartate
- TTP and aspartate
How do the higher concentrations of CTP affect the production of pyrimidine?
- The higher concentrations of CTP inhibit the ATCase enzyme and therefore stop the further synthesis of pyrimidine nucleotides.
- The higher concentrations of CTP inhibit the ATCase enzyme via a feedback mechanism and hence stop the further synthesis of purine nucleotides.
- The higher concentrations of CTP activate the ATCase enzyme, and hence synthesis of pyrimidine nucleotides is enhanced.
- The higher CTP concentrations activate the ATCase enzyme, and hence synthesis of purine nucleotides is enhanced.
- The higher CTP concentrations activate the ATCase enzyme, and hence synthesis of aspartate is enhanced.
Which of the following is true regarding the regulation of ATCase?
- ATCase requires one aspartate to produce carbamoyl aspartate.
- ATC requires one asparagine to produce carbamoyl asparagine.
- It is activated by CTP and ATP.
- It is inhibited by abundant aspartate.
- It is inhibited by ATP.
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Dozent des Vortrages Pyrimidine de novo Metabolism: ATCase Reaction
Kevin Ahern, PhD
Dr. Kevin Ahern is a Professor in the Department of Biochemistry and Biophysics at Oregon State University (OSU), USA.
He obtained his PhD in Biochemistry from Oregon State University. Currently, he teaches courses for health sciences students at OSU.
He is co-author of three Open Educational electronic textbooks on Biochemistry and a Guide to Getting Into Medical School.
Due to his achievements, he earned OSU’s highest teaching recognition, the Elizabeth P. Ritchie Distinguished Professor Award in 2017.
Within Lecturio, Dr. Ahern teaches courses on Biochemistry and on "How to Get into Medical School”.
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It was very clear and explained well- the subject itself is usually hard to explain
